Tumor immunity plays a significant role in the occurrence and development of cancer. Immunotherapy has become a milestone in cancer treatment. Exosomal circRNA have the potential to be noninvasive biomarkers. Several studies showed that exosomal circRNA involved in tumor immunity and cancer immunotherapy resistance. In this review, we summarized the role of exosomal circRNA in regulating tumor immunity and predicting immunotherapy efficacy. Exosomal circRNA has great prospects in the clinical treatment of cancer.
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