对苯二胺对工人肺功能和健康相关生活质量的影响
Effects of p-phenylenediamine on lung function and health-related quality of life of workers
张明 1樊琳 1刘保峰 1刘静 1唐慧晶 1朱宝立 2缪荣明 3方兴林 4方家阳 5赵淑岚 1张美辨 4曾强1
作者信息
- 1. 天津市疾病预防控制中心
- 2. 江苏省疾病预防控制中心
- 3. 无锡市康复医院
- 4. 浙江省疾病预防控制中心
- 5. 浙江省台州市疾病预防控制中心
- 折叠
摘要
目的 分析对苯二胺职业接触人员的肺功能以及健康相关的生活质量情况.方法 选取某染发剂生产企业中使用对苯二胺作为生产原料的染发剂生产车间的接触工人(100人)以及同一企业内不接触对苯二胺的工人(24人)作为主要对象,使用36项健康调查简表(SF-36)对工人的健康相关生活质量问卷进行调查,并进行职业健康检查,肺功能测试指标包括用力肺活量(FVC),1秒钟用力呼气量(FEV1.0),以及FEV1.0/FVC.结果 调查工人中对苯二胺接触组和对照组的收缩压的差异有统计学意义(P＜0.05).接触组的各项肺功能指标FVC、FEV1.0、FEV1.0/FVC都低于对照组,差异有统计学意义(P＜0.05),接触组躯体疼痛(P=0.002)、一般健康状况(P=0.029)、精力(P=0.038)、精神健康(P=0.003)在均低于对照组,差异有统计学意义.结论 对苯二胺职业接触可能会对职业人群肺功能产生潜在危害,并影响工人的健康相关生活质量.
Abstract
Objective To study the effects p-phenylenediamine (PPD) on lung function and health-related quality of life of occupational exposed workers.Methods This study was based on data from a company that produce hair dye containing PPD in China.Workers who exposed to PPD were selected as the study group,and workers un-exposed to PPD were selected as the control group.Questionnaires on health-related quality of life of workers using the 36-item Short Form Health Survey (SF-36).Occupational health examination assessment results were tested in Taizhou Cancer Hospital.The lung function test includes forced vital capacity (FVC),forced expiratory volume in one second (FEV1.0),and ratio of FEV1.0 to FVC (FEV1.0/FVC).Results The difference in systolic blood pressure between the PPD exposed group and the control group was statistically significant (P＜0.05).FVC,FEV1.0,and FEV1.0/FVC of the lung function indexes in the exposed group were lower than those in the control group (P＜0.05).In the health-related quality of life,body pain (P=0.002),general health (P=0.029),vitality (P=0.038),and mental health (P=0.003) were lower in the exposed group than in the control group.Conclusion Occupational exposed to PPD may induce hazard to the workers' lung function and may cause detrimental effect on workers' health-related quality of life.
关键词
对苯二胺/职业暴露/肺功能Key words
p-Phenylenediamine/Occupational exposure/Lung function引用本文复制引用
基金项目
国家卫生与计划生育委员会职业卫生标准项目(20110207)
国家卫生与计划生育委员会职业卫生标准项目(20140704)
天津市自然科学基金青年项目(15JCQN-JC45100)
天津市卫生局科技基金重点项目(2014KR13)
天津市疾病预防控制中心科学院基金(CDCKY601)
出版年
2018
NETL
NSTL
维普
万方数据