首页|晶状体混浊放射工作人员遗传指标及职业特征分析

晶状体混浊放射工作人员遗传指标及职业特征分析

Analysis of cytogenetic indexes and occupational characteristics of radiation workers with lens opacity

扫码查看
目的 了解不同工龄、年龄及工种放射工作人员晶状体混浊情况,分析辐射性晶状体混浊放射工作人员的微核及染色体特点.方法 于2022年1月,选取2014年3月至2021年12月在杭州市职业病防治院进行放射职业健康检查且检查出晶状体混浊的400名放射工作人员为研究对象.分析不同工龄、工种、年龄等放射工作人员眼晶状体混浊比例、外周血淋巴细胞微核异常率及染色体畸变率之间的差异.结果 与工龄<20年放射工作人员微核异常率(0.18‰)和染色体畸变率(0.31%)比较,工龄≥20年放射工作人员外周血淋巴细胞微核异常率(0.59‰)和染色体畸变率(2.67%)更高,差异均有统计学意义(P<0.05);介入放射人员微核率(0.32‰)及染色体畸变异常率(0.57%)高于牙科放射人员(0.12‰和0.19%)和诊断放射人员(0.05‰和0.12%),差异均有统计学意义(x2=23.98、6.72,P<0.05).结论 介入放射人员微核异常率及染色体畸变率高于牙科放射、传统诊断放射人员,放射工作人员必须做好个人防护,定期进行放射职业健康检查.
Objective To analyse the characteristics of micronuclus and chromosomal aberrations and the lens opacity in different working years,ages and work type of radiation workers with lens opacity.Methods In January 2022,we selected 400 radiation workers with lens opacity who had undergone occupational health examination in Hangzhou Hospital for the Prevention and Treatment of Occupational Disease from March 2014 to December 2021 as research objects.To analyze the differences of micronucleus,chromosome aberration and the lens opacification rates of different length of service,type of work,age radiologic workers.Results The results showed that radiation the micronucleus abnormality(0.59‰)and chromosome aberration(2.67%)in peripheral blood in workers who served more than 20 years were significantly higher than that of micronucleus abnormality(0.18‰)and chromosome aberration(0.31%)in workers served less than 20 years,the differences were statistically significant(P<0.05).The micronucleus abnormality(0.32‰)and chromosome aberration(0.57%)in the interventionist were higher than oral radiation workers(0.12‰ and 0.19%)and diagnostic radiologist(0.05‰ and 0.12%),the differences were statistically signcficant(x2=23.98,6.72,P<0.05).Conclusion The rates of micronucleus and chromosome aberration of the interventionaist are higher than oral radiation workers and the traditional radiologist.Workers engaged in radiation should improve personal protection and undertake regular occupational health examinations.

RadiationChromosomesMicronucleiLymphocyteMedical institutionCytogenetic indexOccupational characteristics

边阳甫、钟皓成、金琪、潘萍萍

展开 >

杭州市职业病防治院职业病科,杭州 310014

放射 染色体 微核 淋巴细胞 医疗机构 细胞遗传指标 职业特征

浙江省医药卫生科技计划杭州市医药卫生科技项目

2020KY78320211231Y083

2024

中华劳动卫生职业病杂志
中华医学会

中华劳动卫生职业病杂志

CSTPCD北大核心
影响因子:0.787
ISSN:1001-9391
年,卷(期):2024.42(10)