Objective To study the clinical efficacy of local hyperthermia combined with interventional treatment for liver cancer.Methods From August 1995 to December 1998,20 patients with primary liver cancer(males,age ranged from 34～62 years old,mean 49.2 years old) were locally treated with hyperthermia(using BSD 2000 and Sigma 60 radiator) combined with interventional treatment.The size of tumor was 6 cm ×7 cm×8 cm to 13 cm×15 cm×17 cm.During the hyperthermia,the tumor temperature was directly measured by thermometer with high resistance lead.Each thermotherpy was 40～60 min.Of interventional treatment,the transcatheter arterial chemotherapy(such as PDD 80 mg,5-FU 1.5 g,EADM 50～60 mg) and embolization(using mixture of iodipin and EADM 10 mg) was used and combined with hyperthermia.Results After treatment,the excellent in effects was 30%(6 cases),the effective 35%(7 cases).Median survival interval was 10 months.The survival rate of 1-year was 35%,2-year 10%.75% patients took one hyperthermia,all together,20 cases took 33 times of hyperthermia.The tumor temperature was averagely 41.7℃(40.7～42.7℃).Among them,the temperature over 41.0℃ was 25 times(75.8%).The thermal dose of TEM 42.5℃ was calculated.Conclusion It shows that BSD 2000 heating apparatus and Sigma 60 radiator have better efficacy for primary liver cancer,especially combined with interventional treatment.
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维普
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