Kidney calculi are one of the most common diseases in urology.Vitamin D supplementation can promote intestinal absorption of calcium,and increase the risk of urinary calcium excretion and kidney calculi formation.However,some studies have shown that vitamin D supplementation in the general population was not associated with the risk of kidney calculi.Therefore,whether taking vitamin D may lead to kidney calculi is still a focus issue.This article mainly reviewed the overview of vitamin D and the basic,clinical and mechanistic studies on the relationship between vitamin D and risk of kidney calculi,and proposed that,when vitamin D and calcium supplements were taken in combination,the potential risk of kidney calculi formation should be considered.
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