中华泌尿外科杂志2024,Vol.45Issue(3) :219-220.DOI:10.3760/cma.j.cn112330-20231207-00174

伴合胞体样巨细胞的透明细胞性肾细胞癌1例报告

Clear cell renal cell carcinoma with syncytial giant cells:a case report

孙文佳 岳君秋 樊利芳
中华泌尿外科杂志2024,Vol.45Issue(3) :219-220.DOI:10.3760/cma.j.cn112330-20231207-00174

伴合胞体样巨细胞的透明细胞性肾细胞癌1例报告

Clear cell renal cell carcinoma with syncytial giant cells:a case report

孙文佳 1岳君秋 1樊利芳1
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作者信息

  • 1. 华中科技大学同济医学院附属湖北肿瘤医院病理科,武汉 430070
  • 折叠

摘要

合胞体样巨细胞(SGCs)是指具有多个大小和形状非常相似的细胞核的上皮源性巨细胞.伴SGCs的透明细胞性肾细胞癌(ccRCC)是一种罕见的镜下形态.本文报道1例老年男性患者,因胸部CT检查发现双肺多发结节2周入院.PET-CT检查提示左肾癌伴双肺转移.行减瘤性左肾切除术,病理诊断为伴SGCs的ccRCC.术后行靶向治疗联合免疫治疗,术后随访28个月,疾病无进展.

Abstract

Syncytial giant cells(SGCs)are epithelial giant cells with multiple uniform and similar nuclei.Clear cell renal cell carcinoma(ccRCC)with SGCs is a rare microscopic morphology.A 70-year-old man was admitted to hospital with multiple nodules in both lungs found by chest CT examination 2 weeks before.A left renal carcinoma with lung metastasis was considered by PET-CT.Cytoreductive nephrectomy was performed,and postoperative pathological diagnosis confirmed ccRCC with SGCs of the left renal.Combined immunotherapy and targeted therapies were administered.There was no disease progression during follow-up period of 28 months.

关键词

癌,肾细胞/透明细胞/合胞体样巨细胞/预后

Key words

Carcinoma,renal cell/Clear cell/Syncytial giant cells/Prognosis

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出版年

2024
中华泌尿外科杂志
中华医学会

中华泌尿外科杂志

CSTPCD北大核心
影响因子:1.628
ISSN:1000-6702
参考文献量8
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