Prepubertal-type testicular neuroendocrine tumor is a rare neoplasm of low malignant potential,which is classified as germ cell tumors unrelated to germ cell neoplasia in situ,and needs to be differentiated from metastatic neuroendocrine tumor,postpubertal-type testicular neuroendocrine tumor,and testicular seminoma.The clinicopathological and molecular features of a case of prepubertal-type testicular neuroendocrine tumor were reported.The tumour cells were uniform in size and arranged in nested and insular pattern.The tumor was positive for CgA and Syn,and the Ki-67 index was less than 2％by immunostaining.Next-generation sequencing identified no variants of pathogenicity,potential pathogenicity or uncertain significance.The patient was followed without evidence of recurrence and metastasis 56 months after surgery.
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