首页|可弯曲负压吸引鞘与普通输尿管鞘联合输尿管软镜治疗上尿路结石疗效和安全性的荟萃分析

可弯曲负压吸引鞘与普通输尿管鞘联合输尿管软镜治疗上尿路结石疗效和安全性的荟萃分析

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目的 系统评价可弯曲负压吸引鞘与普通输尿管鞘联合输尿管软镜治疗上尿路结石的疗效和安全性的差异.方法 检索知网、万方、维普、中国生物医学文献数据库、PubMed、Cochrane、Embase、Web of Science、MEDLINE、Google Scholar等数据库中可弯曲负压吸引鞘对比普通输尿管鞘联合输尿管软镜治疗上尿路结石的相关文献,检索时限为建库至2024年5月31日.由2名研究者独立进行文献筛选和数据提取,采用Cochrane风险偏倚评估量表对随机对照研究进行质量评估,采用纽卡斯尔-渥太华风险偏倚评估量表对回顾性研究进行质量评估,采用Review Manager 5.3软件进行荟萃分析.结果 共纳入14篇文献,1 947例上尿路结石患者(可弯曲鞘组1017例,普通鞘组930例).荟萃分析结果显示,可弯曲鞘组清石率高于普通鞘组(术后即刻清石率:80.7%与60.0%,OR=3.04,95%CI 2.30~4.03,P<0.05;术后 1 个月清石率:94.4%与79.4%,OR=4.39,95%CI3.12~6.19,P<0.05);可弯曲鞘组总并发症发生率低于普通鞘组(5.4%与17.3%,OR=0.29,95%CI0.21~0.40,P<0.05);可弯曲鞘组和普通鞘组术后1 d血红蛋白水平下降量差异无统计学意义(MD=-0.30,95%CI-2.61~2.02,P>0.05);可弯曲鞘组术后发热率低于普通鞘组(1.9%与7.5%,OR=0.28,95%CI0.15~0.54,P<0.05);可弯曲鞘组和普通鞘组手术时间差异无统计学意义(MD=-4.93,95%CI-11.48~1.62,P>0.05);可弯曲鞘组术后住院时间短于普通鞘组(MD=-0.20,95%CI-0.25~-0.16,P<0.05).结论 与普通输尿管鞘相比,可弯曲负压吸引鞘联合输尿管软镜治疗上尿路结石的清石率更高、术后发热率更低、总体并发症发生率更低、术后住院时间更短,利于患者术后康复,更安全有效.
Comparison the efficacy and safety of Tip-flexible suction ureteral access sheath and ordinary ureteral access sheath combined with flexible ureteroscopy to treat upper urinary tract stones:a meta-analysis
Objective To systematically evaluate of the efficacy and safety of Tip-flexible suction ureteral access sheath and ordinary ureteral access sheath combined with flexible ureteroscopy to treat upper urinary tract stones.Methods The databases CNKI,Wanfang,VIP,CBM,PubMed,Cochrane,Embase,Web of Science,MEDLINE and Google Scholar were searched from their inception to May 31,2024 for related studies about Tip-flexible suction ureteral access sheath compared with ordinary ureteral sheath combined with flexible ureteroscopy to treat upper urinary tract stones.Literature screening and data extraction were performed independently by two researchers,the quality assessment of randomized controlled trials was assessed using the Cochrane risk of bias assessment scale,the Newcastle-Ottawa risk of bias assessment scale was used to assess the quality of retrospective studies,and finally Meta-analysis of data was conducted using Review Manager 5.3 software.Results A total of 14 literatures involving 1947 patients with upper urinary tract stones(1017 in the Tip-flexible suction sheath group and 930 in the ordinary sheath group)were included.Meta-analysis showed that the stone free rate of the Tip-flexible suction sheath group was higher than that of the ordinary sheath group(immediate postoperative stone free rate 80.7%vs.60.0%,OR=3.04,95%CI2.30-4.03,P<0.05;1 month after surgery stone free rate 94.4%vs.79.4%,OR=4.39,95%CI 3.12-6.19,P<0.05).The total complication rate of the Tip-flexible suction sheath group was lower than that of the ordinary sheath group(5.4%vs.17.3%,OR=0.29,95%CI 0.21~0.40,P<0.05).There was no significant difference in the decrease of hemoglobin level between the Tip-flexible suction sheath group and the ordinary sheath group at 1 day after surgery(MD=-0.30,95%CI-2.61-2.02,P>0.05).The postoperative fever in the Tip-flexible suction sheath group was less than that in the ordinary sheath group(1.9%vs.7.5%,OR=0.28,95%CI 0.15-0.54,P<0.05).There was no significant difference in operation time between the Tip-flexible suction sheath group and the ordinary sheath group(MD=-4.93,95%CI-11.48-1.62,P>0.05).The postoperative hospital stay in the Tip-flexible suction sheath group was shorter than that in the ordinary sheath group(MD=-0.20,95%CI-0.25--0.16,P<0.05).Conclusions Compared with ordinary ureteral access sheath combined with flexible ureteroscope to treat upper urinary tract stones,Tip-flexible suction ureteral access sheath has a higher stone free rate,less postoperative fever,low total complication rate,shorter postoperative hospital stay,which is conducive to postoperative recovery and is safer and more effective.

Tip-Flexible suction ureteral access sheathFlexible ureteroscopyUpper urinary tract stoneEfficacySafety

谢怡杰、丁美旋、龚赫、黄前浩、郑琦、管冰、黄海超、郑嘉欣、段波、王惠强、白培德、陈斌

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厦门大学附属第一医院泌尿外科,厦门 361003

可弯曲负压吸引鞘 输尿管软镜 上尿路结石 疗效 安全性

2024

中华泌尿外科杂志
中华医学会

中华泌尿外科杂志

CSTPCD北大核心
影响因子:1.628
ISSN:1000-6702
年,卷(期):2024.45(10)