首页|包皮环形带蒂皮瓣在复杂性长段尿道狭窄中的应用

包皮环形带蒂皮瓣在复杂性长段尿道狭窄中的应用

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目的 探讨包皮环形带蒂皮瓣治疗复杂性长段前尿道狭窄的疗效.方法 回顾性分析2019年10月至2022年11月上海交通大学医学院附属新华医院采用包皮环形带蒂皮瓣治疗11例复杂性长段前尿道狭窄患者的临床资料.患者年龄40~66岁,平均46岁;尿道狭窄长度6~13 cm,平均7 cm;术前最大尿流率3~7 ml/s,平均5 ml/s.11例既往有反复尿路感染病史及尿路结石腔内治疗手术史.11例均行包皮环形带蒂皮瓣重建尿道,其中1例患者为阴囊坏死性筋膜炎,阴囊段尿道完全毁损缺失,急性期给予膀胱造瘘,手术清创及创面负压封闭引流,6个月后行包皮环形带蒂皮瓣卷管尿道重建;余10例行包皮环形带蒂皮瓣Onlay尿道重建.分析患者最大尿流率变化,是否出现再狭窄、尿瘘、尿道憩室.结果 11例手术均顺利完成.手术时间96~246 min,平均121 min;术中出血量10~200 ml,平均46 ml;住院时间6~13 d,平均9 d;留置导尿时间18~28 d,平均20 d.术后随访9~32个月,平均24个月.11例拔除导尿管后均排尿通畅,拔除导尿管后3个月最大尿流率16.1~24.2 ml/s,平均17.6 ml/s,较术前明显增加.2例术后4周排尿后出现尿道口滴尿,尿道造影检查显示重建段尿道憩室形成.结论 包皮环形带蒂皮瓣尿道重建术是复杂性长段尿道狭窄可选择的治疗方式,手术效果确切,可根据患者自身条件及术者技术水平,进行合理选择.
Application of preputial circular pedicle flap in complex long segment urethral stricture
Objective To explore the application selection of preputial circular flap pedicle in the treatment of complex long segment urethral stricture.Methods The data of 11 patients who underwent surgical reconstruction of the urethra for complex long segment urethral stricture between October 2019 and November 2022 in Xinhua Hospital Affiliated to Shanghai Jiaotong University,School of Medicine were retrospectively analyzed.The patients'average age was 46(range 40-66)years old,with average urethral stricture length of 7(range 6-13)cm and average maximum preoperative urinary flow rate of 5(range 3-7)ml/s.They had a history of recurrent urinary tract infections and endoscopic treatment for urinary tract stones.Among the 11 cases,one patient had necrotizing fasciitis of the scrotum with complete destruction and loss of the scrotal urethra.This patient received acute bladder diversion,surgical debridement,vacuum sealing drainage,and negative pressure suction during the acute phase.And six months later,a circular preputial pedicle flap was used to reconstruct a 12 cm urethral defect in the scrotal region.The remaining 10 patients underwent preputial circular flap pedicle onlay urethral reconstruction.The changes in the patient's maximum urinary flow rate,and the signs of restenosis,urinary fistula,or urethral diverticulum were analyzed.Results All 11 patients who underwent preputial circular flap pedicle urethral reconstruction had unobstructed urination after surgery.Surgical time ranged from 96 to 246 min,with an average of 121 min.The intraoperative blood loss ranged from 10 to 200 ml,with an average of 46 ml.The hospital stay ranged from 6 to 13 d,with an average of 9 d.The indwelling catheterisation time ranged from 18 to 28 d,with an average of 20 d.The patients were followed-up for 9 to 32 months,with an average of 24 months.All 11 cases had smooth urinary flow after surgery,and the maximum urinary flow rate ranged from 16.1 to 24.2 ml/s,with an average of 17.6 ml/s,which was significantly higher than that before surgery.Two patients had post-void dribbling after four weeks,and imaging showed the formation of a diverticulum in the reconstructed segment of the urethra.Conclusions Urethral reconstruction with preputial circular flap pedicle is a viable treatment option for complex long segment urethral stricture.The surgical outcomes are satisfactory,and the choice of treatment should be based on the patients own conditions and the surgeons technical expertise.

Urethral strictureNecrotizing fasciitisUrethral damageUrethral reconstruction

段刘剑、徐艳、曹建伟、张林、崔心刚、李超

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上海交通大学医学院附属新华医院泌尿外科,上海 200092

尿道狭窄 坏死性筋膜炎 尿道毁损 尿道重建

2024

中华泌尿外科杂志
中华医学会

中华泌尿外科杂志

CSTPCD北大核心
影响因子:1.628
ISSN:1000-6702
年,卷(期):2024.45(11)