Patient-derived organoid is an emerging in vitro model in tumor research,highly preserving intratumoral and intertumoral heterogeneity,monitoring patients'response to drugs and other therapies,and guiding precision medicine choice for tumor treatment.This review described the application of patient-derived organoid in drug sensitivity test,cancer biomarkers,validation of new therapies in prostate cancer,bladder cancer,and renal cancer,exhibiting the role of patient-derived organoid in clinical tumor research.
关键词
前列腺肿瘤/膀胱肿瘤/肾肿瘤/类器官/精准医学
Key words
Prostatic neoplasms/Urinary bladder neoplasms/Kidney neoplasms/Organoids/Precision medicine
维普
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