术前衰弱联合营养状况对妇科恶性肿瘤患者延迟性术后肠麻痹的预测价值
Predictive value of preoperative frailty combined with nutritional status for prolonged postoperative ileus in patients with gynecologic malignancies
单蓓莹 1周雨丹 2吴立雪 1祝文澜 1王继文 1庄猛 1孙海建 2张继如1
作者信息
- 1. 江南大学附属医院麻醉科,无锡 214125
- 2. 江南大学无锡医学院,无锡 214125
- 折叠
摘要
目的 评价术前衰弱联合营养状况对妇科恶性肿瘤患者延迟性术后肠麻痹(PPOI)的预测价值.方法 选择2022年4月至2023年2月于江南大学附属医院择期行妇科恶性肿瘤手术患者,入院24 h内采用Frail量表评估衰弱情况,采用控制营养状况评分评估营养状况.记录患者一般资料指标和PPOI发生情况,采用多因素logistic回归分析PPOI的危险因素.采用受试者工作特征曲线评价衰弱、营养状况及两者联合对PPOI的预测能力.结果 最终纳入患者214例,PPOI患者52例,衰弱患者98例.术前衰弱联合中重度营养不良是妇科恶性肿瘤患者PPOI的独立危险因素(P＜0.05),预测妇科恶性肿瘤患者PPOI发生的曲线下面积为0.796(95％CI 0.736～0.857).结论 术前衰弱联合中重度营养不良预测妇科恶性肿瘤患者PPOI的准确性较高.
Abstract
Objective To evaluate the predictive value of preoperative frailty combined with nutri-tional status for prolonged postoperative ileus(PPOI)in the patients with gynecological malignancies.Methods Patients undergoing elective surgery for gynecological malignancies in the Affiliated Hospital of Jiangnan University from April 2022 to February 2023 were selected.The Frail scale was used to evaluate the frailty within 24 h of admission,and the nutritional status was evaluated by the Controlling Nutritional Status score.The general characteristics of patients and occurrence of PPOI were recorded,and the risk fac-tors for PPOI were analyzed by multivariate logistic regression.The ability of frailty,nutritional status and their combination to predict PPOI was assessed by the receiver operating characteristic curve.Results Two hundred and fourteen patients were finally included,52 cases developed of PPOI,and 98 cases were frail patients.Preoperative frailty combined with moderate to severe malnutrition was an independent risk factor for PPOI in the patients with gynecological malignancies(P＜0.05),and the area under the curve in predic-ting the occurrence of PPOI was 0.796(95％confidence interval 0.736-0.857)in the patients with gyneco-logical malignancies.Conclusions Preoperative frailty combined with moderate to severe malnutrition has a higher accuracy in predicting PPOI in the patients with gynecological malignancies.
关键词
衰弱/营养状况/手术后并发症/功能性肠阻塞/生殖器肿瘤,女(雌)性Key words
Frailty/Nutritional status/Postoperative complications/Ileus/Genital neo-plasms,female引用本文复制引用
基金项目
无锡市中青年医疗卫生拔尖人才项目(BJ2023045)
无锡市科技局医疗技术攻关项目(Y20232017)
江南大学附属医院临床研究与转化医学研究项目(LCY202226)
出版年
2024
NETL
NSTL
万方数据