体外受精-胚胎移植患者全身麻醉下卵巢穿刺取卵术后恶心呕吐的影响因素
Influencing factors of postoperative nausea and vomiting in patients undergoing egg retrieval with general anesthesia for in vitro fertilization-embryo transfer
刘金莲 1黄琴 1韩彩凤 1王璐瑜 1王洋 1王明亚 2王洁初2
作者信息
- 1. 北京大学第三医院妇产科生殖医学中心,北京 100191
- 2. 北京大学第三医院麻醉科,北京 100191
- 折叠
摘要
目的 筛选体外受精-胚胎移植(IVF-ET)患者全身麻醉下卵巢穿刺取卵术后恶心呕吐(PONV)的影响因素.方法 本研究为病例对照研究.回顾性收集2020年11月至12月本院生殖医学中心全身麻醉下取卵术的IVF-ET患者病历资料,确定发生PONV患者52例(PONV组),选取未发生PONV患者252例作为对照组(C组).对可疑影响因素进行单因素分析,差异有统计学意义的因素纳入logistic回归分析模型,筛选PONV的影响因素.结果 与C组比较,PONV组患者取卵数、麻醉时间、PONV和/或晕动病史比率差异有统计学意义(P＜0.05);多因素logistic回归分析结果显示:取卵数多、麻醉时间长和PONV和/或晕动病史比率高是PONV的独立危险因素.结论 取卵数多、麻醉时间长和PONV和/或晕动病史比率高是IVF-ET患者全身麻醉下取卵术PONV的独立危险因素.
Abstract
Objective To identify the influencing factors of postoperative nausea and vomiting(PONV)in the patients undergoing egg retrieval with general anesthesia for in vitro fertilization-embryo transfer(IVF-ET).Methods This was a case-control study.Medical records from IVF-ET patients under-going egg retrieval with general anesthesia in the Center for Reproductive Medicine in our hospital from No-vember to December 2020 were retrospectively collected,52 patients with PONV were identified(group PONV),and 252 patients without PONV were selected as control group(group C).Univariate analysis was performed on the suspicious influencing factors,and the factors with statistically significant differences were included in the logistic regression analysis model to identify the influencing factors of PONV.Results Com-pared with group C,statistically significant differences were found in the number of eggs,anesthesia time,and the proportion of PONV history and/or motion sickness history in group PONV(P＜0.05).The results of multivariate logistic regression analysis showed that a large number of eggs,long anesthesia time,and a high proportion of PONV history and/or motion sickness history were independent risk factors for PONV.Conclu-sions A large number of eggs,long anesthesia time,and a high proportion of PONV history and/or motion sickness history are independent risk factors for PONV in IVF-ET patients undergoing egg retrieval with gen-eral anesthesia.
关键词
体外受精/胚胎移植/麻醉,全身/卵子/手术后恶心呕吐/影响因素分析Key words
Fertilization in vitro/Embryo transfer/Anesthesia,general/Ovum/Postoper-ative nausea and vomiting/Root cause analysis引用本文复制引用
基金项目
北京大学第三医院青年孵育基金(BYSYFY2021048)
出版年
2024
NETL
NSTL
万方数据