生物节律因素对体外循环心脏手术后AKI发生的影响:回顾性队列研究
Effects of biorhythm factors on development of acute kidney injury after cardiac surgery using car-diopulmonary bypass:a retrospective cohort study
李小东 1文静 1徐小 1廖先建 1宋雨汐 1段家翔 1鲁开智 1易斌 1甯交琳1
作者信息
- 1. 陆军军医大学第一附属医院麻醉科,重庆 400038
- 折叠
摘要
目的 评价生物节律因素对体外循环心脏手术后急性肾损伤(AKI)发生的影响.方法 本研究为回顾性队列研究.收集2018年6月至2019年12月体外循环心脏手术患者的病例资料,按照实施麻醉手术的时间分为2组(n=125):上午节律组(Ⅰ组)8:00至12:00实施麻醉手术;下午节律组(Ⅱ组)14:00至18:00实施麻醉手术.记录患者术后AKI及术后其他相关并发症(肺部感染、脓毒症、脑梗死)发生情况.结果 与Ⅱ组相比,Ⅰ组术后AKI发生率升高(P＜0.05),相对危险度为3.2(95％置信区间为1.31～7.70),肺部感染、脓毒症和脑梗死发生率差异无统计学意义(P＞0.05).结论 生物节律因素影响体外循环心脏手术后AKI发生,下午较上午实施手术有助于降低术后AKI发生.
Abstract
Objective To evaluate the effects of biorhythm factors on the occurrence of acute kid-ney injury(AKI)after cardiac surgery using cardiopulmonary bypass.Methods This was a retrospective cohort study.Data from patients undergoing heart surgery involving cardiopulmonary bypass from June 2018 to December 2019 were collected and divided into 2 groups(n=125 each)based on the time of anesthesia operation:morning rhythm group(group Ⅰ)and afternoon rhythm group(group Ⅱ).Anesthesia operation was performed from 8:00 to 12:00 in group Ⅰ.Anesthesia was performed from 14:00 to 18:00 in group Ⅱ.The occurrence of postoperative AKI and other postoperative complications(pulmonary infection,sepsis,cerebral infarction)was recorded.Results Compared with group Ⅱ,the incidence of postoperative AKI was significantly increased,the relative risk was 3.2(95％confidence interval 1.31-7.70),and no signifi-cant change was found in the incidence of pulmonary infection,sepsis and cerebral infarction in group Ⅰ(P＞0.05).Conclusions Biorhythm factors affect the development of AKI after cardiac surgery using car-diopulmonary bypass,and performing surgeries in the afternoon rather than the morning helps reduce the risk of postoperative AKI.
关键词
生物节律/体外循环/急性肾损伤/队列研究/心脏手术Key words
Biorhythm/Extracorporeal circulation/Acute kidney injury/Cohort studies/Cardiac procedures引用本文复制引用
基金项目
国家自然科学基金面上项目(82270095)
出版年
2024
NETL
NSTL
万方数据