摘要
急性缺血性脑卒中（AIS）是急诊最常见的疾病之一，具有高病死率、高致残率等特点。静脉溶栓（IVT）作为AIS的一线治疗方案目前应用较为普遍，溶栓后出血转化是常见的并发症之一。溶栓后出血转化的危险因素主要有年龄、体温、高血压等。目前在溶栓后出血转化的危险因素研究的基础上构建的危险预警模型，国外主要有iScore模型、SEDAN模型、THRIVE模型、SITS模型、STARTING-SICH模型、SICHSCORE模型共6种，国内有THRIVE-c模型、Xu团队的模型、常红团队的模型共3种。作为临床医师，掌握溶栓后出血转化的相关危险因素尤为重要。本文主要对近年来溶栓后出血转化危险因素的研究做一综述。
Abstract
Acute ischemic stroke is one of the most common diseases in the emergency department. It is characterized by a high fatality rate and high disability rate. In acute ischemic stroke, intravenous thrombolysis is used widely as a first-line treatment. Hemorrhagic transformation is one of the common complications after thrombolysis, and the main risk factors include age, body temperature, hypertension, etc. Currently, based on the risk factors of hemorrhagic transformation after thrombolysis, there are mainly six foreign models of risk warning, including iScore model, SEDAN model, THRIVE model, SITS model, STARTING-SICH model, and SICH SCORE model; and three domestic models, including THRIVE-c model, model of Xu team, and model of Chang Hong team. As a clinician, it is particularly imperative to recognize the relevant risk factors of hemorrhagic transformation after thrombolysis. This review mainly focuses on the recent progress in the risk factors of hemorrhagic transformation after thrombolysis.
万方数据