摘要
阿尔茨海默病（AD）是主要损害认知和记忆功能的中枢神经系统退行性疾病，AD的发病机制尚未完全阐明，近年研究表明神经炎症反应在AD发病机制中起着关键的作用，Toll样受体4（TLR4）作为AD中神经炎症的一个触发点，为AD的治疗提供了潜在的靶点，本文就此做一综述以期为AD的临床治疗提供参考借鉴。
Abstract
Alzheimer's disease (AD) is a degenerative disease of the central nervous system that mainly damages cognitive and memory functions. The pathogenesis of AD has not been fully elucidated. Recent studies have shown that neuroinflammatory response plays a key role in the pathogenesis of AD. As a trigger point of neuroinflammation in AD, Toll-like receptor 4 (TLR4) provides a potential target for the treatment of AD. This review aims to provide references for clinical treatment of AD.
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