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首发脑梗死患者急性期血管性认知功能障碍的影响因素分析

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目的 探讨首发脑梗死患者急性期发生认知功能障碍的影响因素,为其早期评估和有效干预提供参考依据.方法 选取2017年2月1日-2019年12月31日某院收治的525例首发急性期脑梗死患者作为研究对象,采用蒙特利尔认知评估量表评估其认知功能,根据评估结果分为认知功能障碍组389例和非认知功能障碍组136例,观察比较2组患者的年龄、性别、文化程度等一般资料,脑梗死部位,高血压、糖尿病、高脂血症等既往史.采用单因素、多因素Logistic逐步后退法回归分析首发急性脑梗死患者急性期认知功能障碍的影响因素.结果 首发脑梗死患者急性期认知功能障碍的发生率为74.1%.单因素分析结果显示,年龄、性别、文化程度、脑梗死部位个数、顶叶梗死、颞叶梗死、丘脑梗死、甘油三酯水平在认知功能障碍组与非认知功能障碍组的比较差异有统计学意义.二元多因素Logistic回归结果显示年龄≥55岁、女性、颞叶梗死为首发脑梗死患者急性期发生血管性认知功能障碍的独立危险因素,而大专及以上学历是发生认知功能障碍的保护因素.结论 首发脑梗死患者急性期血管性认知功能障碍的发生率较高.临床工作中应及时识别首发脑梗死患者发生血管性认知功能障碍的危险因素,常规筛查首发急性脑梗死患者的认知功能,及时给予预防和干预,以改善和减缓认知功能障碍的发生.
Influence Factors of Vascular Cognitive Impairment in Acute Stage of First-episode Cerebral Infarction Patients
Objectives To explore the influencing factors of cognitive dysfunction in patients with first-episode cerebral infarction,and provide reference for early assessment and effective intervention.Methods To select 525 patients with the first-episode cerebral infarction in a hospital from February 2017 to December 2019 as research objects.They used Montreal Cognitive Evaluation Tables(MOCA)to evaluate their cognitive functions.Functional disorders(n=389)and non-recognition dysfunction group(n=136),observe the general information of the age,gender,and cultural level of comparison of the two groups of patients.Waiting for previous history.Using single-factor and multi-factor logistic Returning to return to analyze the influencing factors of acute cognitive dysfunction of patients with acute cerebral infarction.Results The incidence of acute period cognitive dysfunction in patients with first-episode cerebral infarction was 74.1%.The analysis results of the single factor showed that the number of age,gender,cultural level,the number of cerebral infarction parts,top lobe infarction,temporal lobe infarction,mound cerebral infarction,and triglyceride level in the cognitive dysfunction group and the non-recognition dysfunction group are comparative.Statistical significance.Binary multi-factor logistic regression results showed that age ≥55.0 years(OR=1.77,95%confident interval(CT):1.14-2.73,P=0.01),women(OR=2.24,95%CI:1.32-3.81,P=0.003),temporal lobe infarction(OR=4.21,95%CI:1.62-10.97,P=0.003)is the independent risk factors of the acute period of the first-episode cerebral infarction patient,and the college degree and above are recognized protection of functional disorders(OR=0.84,95%CI:0.75-0.94,P=0.003).Conclusions The incidence of acute vascular cognitive dysfunction was higher in patients with first-episode cerebral infarction.In clinical work,the risk factors of vascular cognitive dysfunction in patients with first-episode cerebral infarction should be identified in time,the cognitive function of patients with first-episode acute cerebral infarction should be routinely screened,and timely prevention and intervention should be given to improve and slow down the occurrence of cognitive dysfunction.

First-episodeAcute cerebral infarction patientsCognitive dysfunctionInfluence factors

董凯生、陶香君、王颖、李悦、胡文立

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首都医科大学附属北京朝阳医院神经内科,北京市,朝阳区,100020

首发 脑梗死 急性期 血管性认知功能障碍 影响因素

国家自然科学基金面上课题

81271309

2024

中国病案
中国医院协会

中国病案

CSTPCD
影响因子:1.197
ISSN:1672-2566
年,卷(期):2024.25(6)