Logistic Regression Analysis of Mortality Risk Characteristics in Patients with Acute Ischemic Stroke
Objectives This study aims to analyze the mortality risk characteristics of patients with acute ischemic stroke to provide a reference for early intervention.Methods The electronic medical record system was used to extract the front-page information of 6,632 inpatient medical records of patients mainly diagnosed with acute ischemic stroke from January 1,2021 to December 31,2022 in a tertiary hospital.After excluding a few cases that did not meet the research criteria,a total of 6339 cases were studied.Basic patient information,diagnosis and treatment information were included.Univariate analysis and logistic regression model were used to analyze the relationship between each characteristic and death in patients with ischemic stroke.Results Among the 6339 cases that met the study criteria,121 died,with a case fatality rate of 1.91％.Logistic regression analysis showed that patients with the following characteristics:multiple cerebral artery occlusion or stenosis,atrial fibrillation,coronary heart disease,coma,cerebral herniation,pneumonia,and blood transfusion,had thrombolytic procedures lasting longer than 4 hours.Patients who required ventilator support,underwent surgery(such as craniectomy or decompression),experienced hemorrhagic transformation,and had short hospitalization days exhibited risk characteristics associated with death in patients with cerebral infarction,all of which were statistically significant(P＜0.05).Conclusions Patients with ischemic stroke who are comatose,experience brain herniation,develop pneumonia,have atrial fibrillation and coronary heart disease,undergo blood transfusion treatment,require ventilator support,suffer from cerebral hemorrhage transformation,and need neurosurgery,face an increased risk of death.The reduced risk of death in ischemic stroke patients with multiple cerebral artery occlusions and stenosis,as well as a short hospital stay,needs to be considered in light of clinical and data confounding factors.Thrombolytic intervention should be carried out as early as possible in patients with onset of the disease within the golden 4 hours to reduce the number of patients transitioning to critical illness and requiring neurological surgical intervention.
万方数据
维普
