Clinical Value of Ultrasound Detection of Endometrial Thickness in Asymptomatic Postmenopausal Women
Objectives This study aims to investigate the clinical value of ultrasound detection of endometrial thickness in postmenopausal asymptomatic women.Methods Medical cases of 850 female patients who underwent TVS examination in the hospital from January 1,2020 to June30,2023 were collected.Their clinical characteristics were collected and analyzed,including age,menopausal age,endometrial thickness,body mass index(kg/m^2),pregnancy and birth history,and family history of endometrial cancer.All patients underwent transvaginal ultrasound(TVS).Ultrasound evaluation included assessment of endometrial thickness,endometrial echo uniformity,presence or absence of uterine effusion,and endometrial blood flow signal.Endometrial biopsy was performed under hysteroscopy,with benign lesions or changes such as normal endometrial polyps,submucous myoma,proliferative endometrium,endometritis,and atrophic endometrium classified into group A based on pathological diagnosis.Patients with endometrial cancer or endometrial atypical hyperplasia were classified into group B.The ROC curve of endometrial thickness for predicting the risk of endometrial atypical hyperplasia and endometrial cancer was plotted.Results The pathological results of 850 patients with endometrial thickness ≥5mm were divided into group A(808 cases,95.1％)and group B(42 cases,4.9％).The analysis of clinical characteristics of the two groups showed that there were significant differences in menopause age,endometrial thickness and endometrial thickness distribution in group B compared with group A(P＜0.05).There were no differences in age,body mass index(kg/m2),pregnancy time,birth time and family history of endometrial cancer(P＞0.05).ROC curve of endometrial thickness of 850 patients showed that the AUC was 0.842(95％CI:0.788-0.896),sensitivity was 81.0％,specificity was 76.8％,maximum entry index was 0.578,and the detection rates of atypical hyperplasia and endometrial cancer in patients with endometrial thickness≥10.5 mm significantly increased(P＜0.05).TVS examination of the two groups showed that the uneven ratio of endometrial ultrasonic echo signal in group B was significantly higher than that in group A(P＜0.05).There was no significant difference in endometrial blood flow signal and uterine effusion between the two groups(P＞0.05).Conclusions Ultrasound detection is helpful in determining the risk threshold of endometrial thickness for postmenopausal patients with asymptomatic endometrial thickening,providing clinical reference values for managing this condition.
万方数据
维普
