Distribution Characteristics and Drug Resistance Analysis of Pathogens in Patients with Stroke Complicated with Pulmonary Infection in a Tertiary Hospital in Beijing from 2021 to 2023
Objectives This study aims to analyze the distribution and drug resistance of pathogens associated with pulmonary infection in stroke patients admitted to the neurological intensive care unit(NICU)of a tertiary hospital in Beijing,and to provide data support for anti-infection treatment of critically ill patients.Methods A retrospective analysis method was used to retrieve the information of patients hospitalized in neurocritical care from January 1,2021 to December 31,2023 from the medical record system of a tertiary-level A hospital in Beijing.The sputum specimens collected from the laboratory during the patients'hospitalization and the results of clinical drug sensitivity tests were retrieved for analysis.Results A total of 643 strains of pathogenic bacteria were isolated,mainly Gram-negative bacteria,with Klebsiella pneumoniae ranking first.Gram positive cocci were mainly Staphylococcus aureus.The drug sensitivity results showed that vancomycin,linezolid,and teicoplanin had high antibacterial activity against Gram positive cocci.The resistance of non-fermenting bacteria in Gram negative bacteria was slightly more severe.Conclusions Timely understanding of the types and drug resistance changes of pathogens in patients with pulmonary infections in the neurological intensive care unit has important guiding significance for the application of antibiotics in clinical work.
neurological intensive care unitPathogenic bacteriaDrug resistancePulmonary infection
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