Analysis of Risk Factors Related to Hemorrhage Transformation in Patients with Acute Ischemic Stroke without Intravenous Thrombolysis
Objectives To explore the risk factors related to bleeding complications in acute ischemic stroke patients without intravenous thrombolysis and its influence on prognosis,in order to provide guidance for timely and effective observation and clinical intervention,and improve prognosis.Methods A total of 119 patients with acute ischemic stroke who were hospitalized in the department of neurology and neurosurgery from January 1st,2022 to December 31st,2022 were enrolled through HIS system of a hospital,and demographic characteristics,laboratory indicators,past history,comorbidities,treatment operations and clinical prognosis results were obtained from the front page of hospitalization medical records and medical records.And NIHSS score and GCS score and other data.The risk factors of bleeding complications were investigated by univariate analysis and multivariate logistic regression analysis.Results 119 patients with acute ischemic stroke were divided into the hemorrhage group(37 cases,31.1％)according to whether bleeding transformation occurred.There were 82 cases(68.9％)without bleeding.There were statistically significant differences in age,hypertension,atrial fibrillation,digestive tract diseases,alcohol consumption,sepsis,mechanical ventilation,NIHSS score,hemoglobin,length of stay,hospitalization cost,and mortality ratio,P<0.05.Multiple logistic regression analysis showed that age,hypertension,atrial fibrillation and NIHSS score were independent risk factors for bleeding transformation in patients with acute ischemic stroke,P<0.05.Conclusions Patients with acute severe ischemic stroke were at high risk of hemorrhage complications.Old age,hypertension,atrial fibrillation and NIHSS were independent risk factors for complication of hemorrhage.Risk factors could be identified through early warning,so as to carry out timely and effective observation and nursing intervention,in order to improve the prognosis of patients.
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