Research Progress on the Differentiation of Bovine Preadipocytes Using Non Coding RNA
The intramuscular fat content is an important indicator for evaluating beef grade and value.It depends on the proliferation and differentiation of intramuscular preadipocytes.The differentiation of preadipocytes is a highly coordinated process regulated by various factors such as hormones,transcription factors,cytokines,and epigenetic regulation.Non-coding RNA(ncRNA)is a class of epigenetic regulatory factors that do not encode proteins.NcRNAs play an important role in the differentiation of preadipocytes and the identification,function,and regulatory mechanisms of ncRNAs have become a research hotspot in the deposition of bovine fat.On the basis of a brief introduction to the classification and mechanism of action of ncRNAs,this article elaborates in detail on the expression patterns of three types of ncRNAs,including miRNA,lncRNA,and circRNA,in bovine adipose tissue of different breeds and genders,as well as the research progress in precursor adipocyte differentiation.The aim is to lay a data foundation for parsing the mechanism of ncRNA regulating bovine adipocyte differentiation,and provide a theoretical basis for the application of ncRNA in molecular breeding of beef cattle to improve intramuscular fat content in the future.