Using population genomics tools to analyze resequencing data can better combine selection sites with population history,accurately estimate effective population size,population history and population structure,and determine specific genetic sites and variations.This paper briefly describes the whole genome sequencing technology,introduces its main research methods and imple-mentation software in population genomics,discusses the advantages and disadvantages of these methods,and proposes that the de-velopment of new deep learning models and machine learning algorithms may be the direction of improving population genomics research methods in the future.
关键词
全基因组重测序/群体基因组学/进化与驯化/适应
Key words
Whole genome resequencing/Population genomics/Evolution and domestication/Adaptation