Amino Acid Characterization of Donkey FBXL Family Proteins
The importance of the FBXL protein family lies in that as a key component of E3 ubiquitin ligase,it plays a central role in the regulation of cell cycle,protein degradation,signal transduction and other key biological processes,and is essential for main-taining the normal physiological function and health of organisms.In this study,18 members of the FBXL protein family were combed,the sequences of donkey FBXL protein family were collected,known domains were searched,the physicochemical proper-ties,enzymatic hydrolysis sites,primary structure and tertiary structure of proteins were analyzed,and post-translational modifica-tions of proteins were predicted.To provide a theoretical basis for exploring the degradation pathway of ubiquitination protein in-volved in FBXL family and its biological functions in animal reproduction and development.Through analysis,it was found that FBXL3,FBXL13,FBXL21 and other proteins were related to circadian clock genes.Therefore,these genes can be further studied,which is likely to affect the reproductive cycle regulation of donkeys.
万方数据
维普
