Effect of mannitol combined with oral rehydration salts on intestinal function recovery and intestinal cleanliness in elderly patients undergoing radical surgery of breast cancer
Objective To explore the effect of mannitol combined with oral rehydration salts on intestinal function recovery and intestinal cleanliness in elderly patients undergoing radical mastectomy. Methods From October 2018 to March 2019, 80 patients with breast cancer undergoing radical mastectomy in the First Affiliated Hospital of Hebei North University were randomly divided into control group ( 40 cases ) and observation group (40 cases). The control group took 20％ mannitol injection and the observation group used oral rehydration salts additionally for intestinal preparation. Defecation, intestinal cleanliness, blood glucose, electrolytes, postoperative first anal exhaust time and adverse reactions were analyzed. Results There were no significant differences in the first defecation time and clear defecation time between groups(both P>0. 05). Defecation frequency in observa-tion group was significantly less than those in control group[(4. 7 ± 1. 4) vs (5. 6 ± 2. 5)](P<0. 05). Intestinal cleaning rate in observation group was significantly higher than that in control group[85. 0％(34/40) vs 65. 0％(26/40)](P<0. 05). Postoperative blood glucose level in observation group was significantly lower than that in controlgroup[(5.3±1.1)mmol/Lvs(6.8±1.4)mmol/L](P <0.05). LevelsofNa+,K+ andCl- in observation group were higher than those in control group[(136. 9 ± 1. 0) mmol/L vs (135. 6 ± 1. 1) mmol/L, (4. 1 ± 0. 5)mmol/L vs (3. 7 ± 0. 6)mmol/L, (102. 8 ± 2. 1)mmol/L vs (99. 8 ± 2. 4)mmol/L](all P<0. 05).The first anal exhaust time in observation group was significantly shorter than that in control group[(29 ± 8)h vs (39 ± 12)h](P<0. 05). Incidence of adverse reactions in observation group was significantly lower than that in control group[7. 5％ (3/40) vs 25. 0％ (10/40)](P < 0. 05). Conclusion Mannitol combined with oral rehydration salts for intestinal preparation before radical mastectomy shows good intestinal cleaning effect, as well as can stabilize blood sugar and electrolytes, promote intestinal function recovery and reduce adverse reactions in elderly patients.
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NSTL
万方数据
维普
