Analysis of the influencing factors of critically ill and pregnancy outcomes of pregnant patients with influenza
Objective To analyze the influencing factors of critically ill and pregnancy outcomes of pregnant patients with influenza.Methods A total of 121 pregnant women with influenza in Maternal and Child Health Care of Guangxi Zhuang Autonomous Region from January 2022 to December 2023 were selected as the observation objects.According to the severity of the disease,the patients were divided into general group(64 cases)and critical group(57 cases).Univariate and multivariate Logistic regression methods were used to analyze the influencing factors of critical illness during pregnancy with influenza.The pregnancy outcomes of the patients were counted and analyzed.Results There were statistically significant differences between the two groups in whether they were vaccinated,whether they had severe respiratory symptoms,lymphocyte count,C-reactive protein(CRP)and lactate dehydrogenase(LDH)levels(all P＜0.05).The results of multivariate Logistic regression analysis showed that unvaccinated[odds ratio(OR)=3.105,95％confidence interval(CI):1.345-7.170],severe respiratory symptoms(OR=2.085,95％CI:1.098-3.958),high CRP level(OR=4.011,95％CI:1.572-10.236)and high LDH level(OR=1.806,95％CI:1.131-2.885)were risk factors for critical illness in pregnant women with influenza,and high lymphocyte level(OR=0.894,95％CI:0.831-0.961)was a protective factor for critical illness in pregnant women with influenza(all P＜0.05).All pregnancies in the critical group were terminated during hospitalization for influenza,and no congenital malformations were found in the neonates of the two groups.The preterm birth rate and full-term birth rate in the critical group were higher than those in the general group[61.4％(35/57)vs 4.7％(3/64),29.8％(17/57)vs 9.4％(6/64)],and the continuing pregnancy rate was lower than that of the general group[0(0)vs 82.8％(53/64)](all P＜0.05).Conclusion The severity of influenza can affect the pregnancy outcome of patients.Vaccination,the severity of respiratory symptoms,lymphocyte count,CRP and LDH levels are all factors affecting the critical illness of pregnant patients with influenza.Effective measures should be taken in time to avoid the occurrence of critical illness.
万方数据
维普
