Clinical effect of Lifei capsules combined with theophylline sustained-release tablets in the treatment of chronic asthmatic bronchitis
Objective To investigate the clinical effect of Lifei capsules combined with theophylline sustained-release tablets in the treatment of chronic asthmatic bronchitis.Methods A total of 90 patients with chronic asthmatic bronchitis admitted to Shanxi Cancer Hospital from March 2022 to December 2023 were selected as the research objects.According to the random number table method,90 patients were divided into the control group and the observation group,45 cases in each group.The control group was treated with theophylline sustained-release tablets on the basis of basic treatment,and the observation group was treated with Lifei capsules combined with theophylline sustained-release tablets on the basis of basic treatment.The total effective rate,improvement time of clinical symptoms,blood gas indexes,inflammatory factors and incidence of adverse drug reactions were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group[93.3％(42/45)vs 77.8％(35/45)](P=0.036).The improvement times of wheezing,cough and phlegm in the observation group were shorter than those in the control group(all P＜0.05).After treatment,the levels of arterial partial pressure of oxygen in the two groups were higher than those before treatment,and that in the observation group was higher than that in the control group.The levels of arterial partial pressure of carbon dioxide,C-reactive protein,interleukin-6 and procalcitonin were lower than those before treatment,and those in the observation group were lower than those in the control group(all P＜0.05).There was no significant difference in the incidence of adverse drug reactions between the two groups(P=0.609).Conclusion Lifei capsules combined with theophylline sustained-release tablets can achieve good clinical effect in the treatment of chronic asthmatic bronchitis,which can effectively improve the blood gas indexes and inflammatory response in the body,and has good safety.
万方数据
维普
