Analysis on the Instructions of Chinese Patent Medicines Containing Polygoni Multiflori Radix in Chinese Pharmacopoeia 2020 Edition and Application Situation in Shandong Provincial Hospital Affiliated to Shandong First Medical University
Objective:To analyze the instructions of Chinese patent medicines(CPMs)containing Polygoni Multiflori Radix(PMR)contained in Chinese Pharmacopoeia 2020 edition and the actual drug use in the Shandong Provincial Hospital Affiliated to Shandong First Medical University.Methods:CPMs containing PMR were consulted in Chinese Pharmacopoeia(2020 edition),and 16 items of information including the instruction content and daily dose of PMR were counted.The medical records of CPMs containing PMR in our hospital were inquired,and the medication and adverse reactions were analyzed.Results:A total of 71 kinds of CPMs containing PMR were collected in Chinese Pharmacopoeia,with numbers of problems in their instructions,especially the lack of"medicine for the elderly".The daily dose of PMR components of 3 kinds of CPMs like Shengxuebao mixture exceeded the maximum recommended dose of pharmacopoeia.There were few adverse reactions records of Shengxuebao mixture in our hospital and no reports of serious cases such as liver injury.Conclusion:It is urgent to solve the problem of missing items in the instructions of CPMs with PMR as the monarch medicine.Additionally,attention should be paid to drug education for patients.
Chinese PharmacopoeiaPolygoni Multiflori RadixChinese patent medicinesinstructionsdrugs safety
NETL
NSTL
万方数据
