Study on Candidate Constituents of Quality Markers about Ethnic Drug Desmodium caudatum
Objective:To study the chemical constituents of the leaves of Desmodium caudatum(Thunb.)DC.,a medicinal plant of legume,in order to provide material basis for the establishment of quality standard system for D.caudatum.Methods:After the leaves of Desmodium caudatum(Thunb.)DC.were extracted by 70％ethanol,the chemical constituents of the leaves of D.caudatum were separated and purified by macroporous adsorption resin column chromatography,silica gel column chromatography,and preparative high performance liquid chromatography(HPLC),and their structures of the compounds were identified according to the physicochemical properties and spectral data of the monomers obtained.Results:Thirteen compounds were isolated from the leaves of D.caudatum,these compounds were identified and identified from the leaves of Desmodium caudatum(Thunb.)DC.:desmodol(1),citrusinol(2),8-prenylquercetin(3),dihydrokaempferol(4),neophellamuretin(5),yukovanol(6),quercetin(7),kaempferol(8),vitexin(9),swertisin(10),soyasapogenel B(11),hibiscone A(12)and hibiscone D(13).Among them,compounds 7,8,12 and 13 were the constituents contained in various medicinal parts of D.caudatum.Conclusion:Compounds 7,8,12 and 13 can be used as candidate quality control onstituents of D.caudatum.
NETL
NSTL
万方数据
