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医疗机构他汀类药品评价指标体系的构建

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目的:构建医疗机构他汀类药品评价指标体系,推动临床他汀类药品评价及遴选工作系统化、科学化和规范化.方法:参照《药品临床综合评价管理指南(2021年版试行)》,结合他汀类药品特点及临床用药经验,采用德尔菲法构建他汀类药品多准则、多维度的评价指标体系.结果:在制定的初始评价指标体系的基础上,通过两轮专家问卷咨询,最终确定了他汀类药品评价指标体系,包含6项一级指标,23项二级指标,44项三级指标.两轮专家函询的熟悉程度均为0.81,判断系数分别为0.94、0.95,权威系数分别为0.84、0.88;信度分别为0.95、0.98.结论:本研究构建的他汀类药品评价指标体系科学性较强、权威性较高,能够为医疗机构他汀类药品目录遴选及合理使用、加快药学服务高质量发展、控制不合理药品费用支出等提供重要依据.
Construction of Evaluation Index System of Statins in Medical Institutions
Objective:To construct the evaluation index system of statins in medical institutions and promote the evaluation and selection of clinical statins more systematicly,scientificly and standardizedly. Methods:Referring to "Guidelines for the Management of Comprehensive Clinical Evaluation of Drugs (2021 version trial)",combined with the characteristics of statins and clinical experience,a multi-criteria and multi-dimensional evaluation index system for statins was constructed by using the Delphi method. Results:On the basis of the established initial evaluation index system,the evaluation index system of statins was finally determined through two rounds of expert questionnaire consultation,including 6 first-grade indexes,23 second-grade indexes and 44 third-grade indexes. The familiarity of the two rounds of expert correspondence was 0.81,the coefficient of judgment was 0.94 and 0.95,and the coefficient of authority was 0.84 and 0.88,respectively. The reliability was 0.95 and 0.98,respectively. Conclusion:The evaluation index system of statins established in this study is scientific and authoritative,which can provide an important basis for the selection and rational use of statins catalog in medical institutions,accelerate the high-quality development of pharmaceutical services,and the control of unreasonable drug expenses.

statinsclinical comprehensive evaluationindex systemDelphi method

庞静静、钱雅婷、袁冬冬、刘伟

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郑州市第七人民医院,郑州 450000

郑州大学药学院,郑州 450001

他汀类药品 临床综合评价 指标体系 德尔菲法

2024

中国药事
中国食品药品检定研究院(中国药品生物制品检定所)

中国药事

CSTPCD
影响因子:0.844
ISSN:1002-7777
年,卷(期):2024.38(12)