Biological Characteristics of 25-Hydroxy vita min D3 and Its Application in the Production of Pig and Poultry
25-hydroxyvitamin D3(25-OH-D3),also known as 25-hydroxycholecalciferol and calcium glycol,was the active form of vita-min D3 and the main form of vitamin D3 exists in blood circulation.At present,numerous studies have found that 25-OH-D3 has a higher biological potency compared to vitamin D3,especially when animals were in a challenging environment,oxidative damage or liver func-tion impairment,the supplementation of 25-OH-D3 in diet could improve animal performance,promote bone development,enhance the body's immune function and alleviate oxidative stress,etc.Therefore,this review elucidated the metabolic characteristics,mechanism of action and biological functions of 25-hydroxyvitamin D3,including the regulation of calcium and phosphorus balance,participation in cell proliferation and differentiation,as well as the role on the immune function and antioxidant capacity;and explored the current application of 25-OH-D3 in the production of pig and poultry,with the aim of providing theoretical guidance and reference for the further study of its mechanism of action in animal and its promotion and application in the pig and poultry's production.
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