The study aimed to explore the molecular mechanisms underlying the growth and developmental differences among these pig breeds.Five Neijiang(NJ)pigs and approximately five Yorkshire(YS)pigs were selected for whole-genome resequencing.Differential single-nucleotide polymorphisms(SNPs)were identified through a 10 kb window sliding in 1 kb increments using the Fst method.Ulti-mately,a total of 48 924 non-synonymous single-nucleotide polymorphism sites(nsSNPs)were discovered between NJ and YS pjgs,significantly impacting 2 490 genes.Moreover,three nsSNPs were identified in the genes ACAT1,IGF2R and IGF2BP3,potentially af-fecting the normal functioning of insulin signaling pathways and the conversion of acetyl-CoA to acetoacetyl-CoA.In conclusion,these findings contributed essential knowledge about genetic variations influencing phenotypic features in pigs.
维普
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