首页|金银花源miR2911靶向PEDV基因区域分析

金银花源miR2911靶向PEDV基因区域分析

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金银花源miR2911是一种丰度较高、性质稳定的抗病毒分子,在抗流感病毒感染和SARS-CoV-2感染中发挥着关键作用.然而,有关miR2911靶向PEDV基因区域的研究却鲜有报道.因此,本研究旨在分析miR2911靶向PEDV的基因区域,进一步分析miR2911靶点在不同流行毒株中的保守性.利用miRanda软件成功预测miR2911在PEDV基因组中存在多个靶点,靶向PEDV基因区域保守性很高.为后续深入研究miR2911在抗猪源病毒感染的机理提供了数据支撑.
Analysis of Honeysuckle miR2911 Targeting Gene Regions of PEDV
Honeysuckle source miR2911,a highly abundant and stable antiviral assay that played a key role in fighting against influenza virus and SARS-CoV-2 infection.However,studied on miR2911 targeting gene regions of PEDV had rarely been reported.In this study we aimed to analyze the gene regions of miR2911 targeting PEDV,and make a further analysis of the conservation of miR2911 targets in different epidemic strains.The miRanda software was used to successfully predict the presence of multiple targets of miR2911 in the genomes of PEDV.The results showed that the gene regions targeting PEDV were highly conserved.It could provide important support-ing data for the subsequent in-depth study of the mechanism of miR2911 in the anti-swine virus infection.

pigsPEDVmiR2911viral genestarget areaHoneysuckleantiviral

张秦川、李云辉、张满义、薛嘉熹、孙雪梅、张自瑞、乔亚萱、刘伟楠、蒋松、肖非、高宏伟、孙延鸣、盛金良、张彦兵

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石河子大学动物科技学院,新疆石河子 832003

新疆方牧生物科技有限公司,新疆图木舒克 844000

新疆泰昆集团股份有限公司,新疆昌吉 831203

生猪 PEDV miR2911 病毒基因 靶向区域 金银花 抗病毒

新疆维吾尔自治区青年科学基金项目石河子大学高层次人才科研启动项目石河子大学青年创新培育人才项目动物生物医药兵团重点实验室开放性课题

2022272375RCZK202043CXPY202211FMOF2023002

2024

中国猪业
中国农业科学院农业信息研究所

中国猪业

影响因子:0.241
ISSN:1673-4645
年,卷(期):2024.19(1)
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