Evaluation of Immune Antibodies for Porcine Foot-and-Mouth Disease Inactivated Vaccines in Large-Scale Pig Farms
In order to understand the immunization effect of porcine foot-and-mouth disease(FMD)inactivated vaccines produced by different animal biological product companies and to better carry out immune prevention of porcine FMD,two types of porcine FMD in-activated vaccines were selected from four different companies.These included porcine FMD type O inactivated vaccine and porcine FMD OA bivalent inactivated vaccine.A total of 6 000 healthy and age-appropriate piglets were immunized,with each company vacci-nating 1 500 piglets.The piglets were first vaccinated at 60 days,strengthening immunity at 90 days.Blood samples were collected be-fore and after immunization from four groups of pigs,respectively the first immunization(60 days),after the first immunization 30 days(90 days),30 days after the second vaccination(120 days old),60 days after the second vaccination(150 days old),and 90 days after the second vaccination(180 days old).4 mL whole blood were collected randomly from each group,and after serum separation,anti-body testing was conducted to evaluate the antibody growth and decline rule.The results showed that for the porcine FMD type O inac-tivated vaccine,the antibody evaluation effect of Company A was superior to Company B.Regarding antibody dispersion,Company A showed better results than Company B.As for the porcine FMD OA bivalent inactivated vaccine,the antibody evaluation effect of Com-pany C was superior to Company D.However,the difference in antibody dispersion between Company C and Company D was not sig-nificant.
pigfoot-and-mouth diseasetype O inactivated vaccineOA bivalent inactivated vaccineimmune effect
万方数据
维普
