Expert consensus on clinical application of aminolevulinic acid photodynamic therapy in non-melanoma skin cancers(2025 edition)
Non-melanoma skin cancers(NMSCs)are a common type of malignant tumors including actinic keratosis(precancerous lesions),Bowen's disease,cutaneous squamous cell carcinoma,basal cell carcinoma and extramammary Paget's disease.They pose significant health risks and their incidence rates have been increasing year by year.As one of the important treatment methods for NMSCs,aminolevulinic acid photodynamic therapy(ALA-PDT)can be applied throughout the entire treatment process to achieve comprehensive effects involving prevention,treatment,and rehabilitation,and has been widely applied in clinical practice.To provide evidence-based,practical,and standardized guidance for the clinical application of ALA-PDT in treating NMSCs,the Chinese Association of Rehabilitation Dermatology,the Chinese Association of Photodynamic Therapy and Rehabilitation,and the Photodynamic Therapy Cooperation Center,Chinese Society of Dermatology convened a panel of experts from relevant fields,and developed this consensus based on a thorough review of Chinese and international literature,existing consensus and guidelines,expert clinical experience,and the current status of diagnosis and treatment of NMSCs in China.
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