摘要
脂溢性皮炎是一种慢性、复发性、炎症性皮肤病,其病因与皮肤微生态失调、脂质代谢异常、皮肤屏障功能受损、免疫反应异常以及遗传因素密切相关.近年来许多新的治疗方法如外用磷酸二酯酶4抑制剂、Janus激酶抑制剂、物理治疗和化学剥脱术等为脂溢性皮炎的治疗提供了更多选择.本文综述了脂溢性皮炎在发病机制和治疗方面的最新研究进展.
Abstract
Seborrheic dermatitis is a chronic,recurrent,and inflammatory skin disease.Its etiology is intricately related to skin microecological imbalance,dysregulated lipid metabolism,impaired skin barrier function,abnormal immune responses,and genetic predispositions.In recent years,several novel therapeutic approaches have emerged,such as topical phosphodiesterase 4 inhibitors,Janus kinase inhibitors,physical interventions,and chemical peeling,providing more options for the treatment of seborrheic dermatitis.This review summarizes the latest research progress in the pathogenesis and treatment of seborrheic dermatitis.
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