中华普通外科杂志2024,Vol.39Issue(7) :527-533.DOI:10.3760/cma.j.cn113855-20230818-00067

3D打印指导下开窗/分支支架治疗胸腹主动脉病变:全国多中心回顾性研究

3D print-guided fenestration/branch stent treatment of abdominal aortic disease:a national multicenter retrospective study

韩月雪 金怡 付东生 胡健航 段剑锋 孙莉莉 王冕 于浩 苏奕明 华正东 陈志丹 郭世奎 化召辉 李晓强 刘昭
中华普通外科杂志2024,Vol.39Issue(7) :527-533.DOI:10.3760/cma.j.cn113855-20230818-00067

3D打印指导下开窗/分支支架治疗胸腹主动脉病变:全国多中心回顾性研究

3D print-guided fenestration/branch stent treatment of abdominal aortic disease:a national multicenter retrospective study

韩月雪 1金怡 1付东生 1胡健航 1段剑锋 1孙莉莉 1王冕 2于浩 3苏奕明 4华正东 5陈志丹 6郭世奎 7化召辉 8李晓强 1刘昭1
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作者信息

  • 1. 南京大学医学院附属鼓楼医院血管外科,南京 210008
  • 2. 中山大学附属第一医院血管外科,广州 510062
  • 3. 南部战区总医院心血管外科,广州 510010
  • 4. 柳州市工人医院血管外科,柳州 545005
  • 5. 武汉亚洲心脏病医院心脏中心,武汉 430056
  • 6. 襄阳市中心医院血管外科,襄阳 441021
  • 7. 云南省第一人民医院血管外科,昆明 650032
  • 8. 郑州大学第一附属医院腔内血管外科,郑州 450052
  • 折叠

摘要

目的 探讨应用3D打印技术指导开窗/分支支架技术(fenestrated/branched endovascular repair,F/B-EVAR)血管腔内修复胸腹主动脉疾病的经验.方法 回顾性分析2018年2月至2023年3月全国范围内69家医疗中心采用3D打印技术指导医师自制支架行F/B-EVAR修复胸腹主动脉病变共316例患者的临床及随访资料.结果 本组中位随访时间23个月(2~60个月),随访丢失24例,随访率92.4%(292/316),平均术后住院时间(8.2±4.9)d,共重建胸腹主段分支动脉944条.术中11条分支动脉重建失败,成功率98.8%(933/944).术后30d内,死亡8例,死亡率2.5%,随访中死亡6例,共死亡14例,死亡率4.4%(14/316).脊髓缺血11例(3.5%),无永久性截瘫.术后肾功能损伤19例(6.0%).术后26例患者检查中发现内漏,内漏率8.2%.结论 3D打印技术可对分支动脉位置个体化精准定位,同时简化手术流程,缩短学习曲线且临床疗效较佳.

Abstract

Objective To study the application of 3D printing technology in multi-center fenestrated/branched endovascular repair(F/B-EVAR)for endovascular repair of abdominal aortic diseases.Methods From Feb 2018 to Mar 2023,The clinical and followup data of 316 cases of abdominal aortic lesions undergoing repair with F/B-EVAR at 69 medical centers nationwide using 3D printing technology to guide physician-modified stent graft were retrospectively analyzed.Results The mean follow-up time of the patients was 23 months(2-60 months),and 24 cases were lost to follow up,the follow-up rate was 92.4%(292/316),the mean postoperative hospitalization time was(8.2±4.9)days.A total of 944 main abdominal branch arteries were reconstructed.Intraoperative reconstruction of 11 branches failed,with a success rate of 98.8%(933/944).Within 30 days after surgery,8 patients died(2.5%),and 6 patients died during follow-up,a total of 14 patients died(4.4%).There were 11 cases(3.5%)of spinal cord ischemia and no patient suffered from permanent paraplegia.There were 19 patients(6.0%)with postoperative renal function injury.Internal leakage was found in 26 patients,and the rate of internal leakage was 8.2%.Conclusion 3D printing technology can accurately locate the location of branch arteries,simplifing the surgical process,shortening the learning curve,and improving clinical efficacy.

关键词

主动脉瘤,腹/主动脉瘤,胸/3D打印/开窗分支支架技术

Key words

Aortic aneurysms,abdominal/Aortic aneurysms,thoracic/3D printing/Fenestrated and branched endovascular aortic repair

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基金项目

国家自然科学基金(82370520)

江苏省卓博计划(2022ZB689)

南京鼓楼医院临床研究专项(2023-LCYJ-PY-23)

出版年

2024
中华普通外科杂志
中华医学会

中华普通外科杂志

CSTPCD北大核心
影响因子:1.11
ISSN:1007-631X
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