中华普通外科杂志2024,Vol.39Issue(8) :584-589.DOI:10.3760/cma.j.cn113855-20231111-00321

腹腔镜右半结肠癌全结肠系膜切除术后胃瘫综合征的影响因素分析

Risk factors of postsurgical gastroparesis syndrome after complete mesocolic excision for right colon cancer

田震 程一帆 李瑞奇 周家杰 赵帅 王伟 汤东 任俊 孙倩男 王道荣
中华普通外科杂志2024,Vol.39Issue(8) :584-589.DOI:10.3760/cma.j.cn113855-20231111-00321

腹腔镜右半结肠癌全结肠系膜切除术后胃瘫综合征的影响因素分析

Risk factors of postsurgical gastroparesis syndrome after complete mesocolic excision for right colon cancer

田震 1程一帆 1李瑞奇 1周家杰 1赵帅 1王伟 2汤东 2任俊 2孙倩男 3王道荣1
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作者信息

  • 1. 南京大学医学院教学医院苏北人民医院,扬州 225001
  • 2. 江苏省苏北人民医院胃肠外科,扬州 225001
  • 3. 扬州市消化病/代谢病基础与临床转化重点实验室,扬州 225001
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摘要

目的 探究腹腔镜右半结肠癌全结肠系膜切除术后胃瘫综合征(PGS)的影响因素.方法 回顾性分析358例接受腹腔镜右半结肠癌全结肠系膜切除术患者的临床资料.采用单因素及多因素Logistic回归分析PGS的独立危险因素.结果 本组358例患者中19例患者(4.8%)发生PGS.Logistic回归分析结果显示,术前焦虑评分(PAS-7)≥14(OR=6.450,P=0.039)、术前血清白蛋白<35 g/L(OR=9.302,P=0.011)、肝曲结肠癌(OR=9.782,P=0.007)、No.206组淋巴结清扫(OR=8.317,P=0.004)及术后腹腔感染(OR=5.755,P=0.043)是PGS发生的独立危险因素.结论 腹腔镜右半结肠癌全结肠系膜切除术后胃轻瘫与患者的营养状况、肿瘤位置、淋巴结清扫范围及术后腹腔感染等多种因素有关,应针对性处理.

Abstract

Objective To investigate the risk factors for postsurgical gastroparesis syndrome(PGS)after laparoscopic complete mesocolic excision(CME)for right colon cancer.Methods The clinical data of 358 patients who underwent laparoscopic CME for right colon cancer were retrospectively analyzed.Univariate and multivariate logistics regression were used to analyze the independent risk factors for PGS.Results PGS occurred in 19 patients(4.8%).Logistic regression analysis showed that preoperative anxiety score(PAS-7)≥14(OR=6.450,P=0.039),preoperative serum albumin<35 g/L(OR=9.302,P=0.011),colon cancer at hepatic flexura(OR=9.782,P=0.007),No.206 group lymph node dissection(OR=8.317,P=0.004),and intra-abdominal infection(OR=5.755,P=0.043)were independent risk factors for PGS.Conclusion Patient's preoperative health status,tumor location,scope of lymph node dissection and postoperative intra-abdominal infection are all risk factors related to PGS after CME for right colon cancer.

关键词

结肠肿瘤/胃肌轻瘫/结肠切除术/危险因素

Key words

Colon neoplasms/Gastroparesis/Colectomy/Risk factors

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基金项目

国家自然科学基金资助项目(82373014)

消化病/代谢病基础与临床转化重点实验室项目(YZ2020159)

出版年

2024
中华普通外科杂志
中华医学会

中华普通外科杂志

CSTPCDCSCD北大核心
影响因子:1.11
ISSN:1007-631X
参考文献量18
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