Objective To explore the clinical features,treatment and prognosis of patients with pneumatosis cystoides intestinalis(PCI).Methods The clinical data of 25 PCI patients at Peking University People's Hospital admitted from Jan 2011 to Dec 2020 were retrospectively analyzed.Results Among these 25 PCI patients,there were 9 males and 16 females with a median age of 69(55-78)years.Six patients were asymptomatic,while the main complaint of the remaining patients was abdominal pain(12 cases),followed by diarrhea(4 cases),constipation(2 cases),and abdominal distension(1 case).Fifteen patients with PCI also had hypoalbuminemia.The main radiological manifestation of PCI was the presence of multiple gas-filled cysts within the intestinal wall,with 23 cases occurring in the colon and 17 cases combined with free intra-abdominal gas.All patients were cured with conservative treatment,with no PCI-related deaths during follow-up.Conclusions PCI is a rare gastrointestinal disease with atypical clinical manifestations.Conservative management is an effective treatment with good prognosis.
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