肝脏未分化胚胎性肉瘤的诊断及治疗
Diagnosis and treatment of undifferentiated embryonal sarcoma of the liver
李振 1刘婧 2王云慧 1孔文青 3陈新国 4赖建君 5李启龙 6马邦振4
作者信息
- 1. 青岛大学附属烟台毓璜顶医院普外儿外科,烟台 264000
- 2. 青岛大学附属烟台毓璜顶医院病理科,烟台 264000
- 3. 青岛大学附属烟台毓璜顶医院中区手术室,烟台 264000
- 4. 山东第一医科大学附属省立医院儿外科,济南 250000
- 5. 山东第一医科大学附属省立医院外科门诊,济南 250000
- 6. 山东第一医科大学附属省立医院统计与病案管理科,济南 250000
- 折叠
摘要
目的 总结肝脏未分化胚胎性肉瘤的临床病理特点.方法 回顾性分析山东省立医院及烟台毓璜顶医院综合性医学中心2000年1月至2023年1月收治的16例肝脏未分化胚胎性肉瘤患者的临床资料.结果 16例患者均经病理明确证实.症状以腹部包块、腹痛不适为主,实验室检查无特异性肿瘤学指标,影像检查多以囊实性成分为主.14例行根治性手术切除,术后最短生存时间7个月,最长时间121个月,中位生存时间35.9个月.结论 肝脏未分化胚胎性肉瘤是一种极其罕见的肝脏恶性肿瘤,临床表现不典型,CT检查有助于诊断.确诊需病理检查.该病患者预后较差,手术切除是有效的治疗手段.
Abstract
Objective To summarize the clinicopathologic characteristics of undifferentiated embryonal sarcoma of the liver.Methods The clinical data of 16 patients with undifferentiated embryonal sarcoma of the liver admitted to Shandong Provincial Hospital and Yantai Yuhuangding Hospital from Jan 2000 to Jan 2023 was retrospectively analyzed.Results The diagnosis of undifferentiated embryonal sarcoma in all the 16 patients was established by postoperative pathology.The clinical manifestations of the patients were mainly asymptomatic abdominal mass,abdominal pain and discomfort.The laboratory examination was mostly nonspecific,the image exam showed mostly solid cystic mass.14 cases underwent radical surgical resection.The minimum survival time was 7 months,maximum survival time was 121 months with median survival time of 35.9 months.Conclusions Undifferentiated embryonal sarcoma of the liver is an extremely rare malignant tumor of the liver.The disease lacks specific clinical manifestations.CT examination can assist in the diagnosis of the disease.Diagnosis of undifferentiated embryonal sarcoma of the liver depends on pathological examination.The prognosis of patients is poor,surgical resection of the tumor is an effective treatment.
关键词
肝肿瘤/肉瘤/诊断/治疗Key words
Liver neoplasms/Sarcoma/Diagnosis/Treatment引用本文复制引用
基金项目
山东第一医科大学(山东省医学科学院)青年科学基金培育资助计划(202201-051)
出版年
2024
NETL
NSTL
万方数据