环境因素对甲状腺癌发病率的影响
Environmental influences on the increased incidence rate of thyroid cancer
刘文 1程若川1
作者信息
- 1. 昆明医科大学第一附属医院甲状腺外科云南省甲状腺外科临床研究中心,昆明 650032
- 折叠
摘要
甲状腺癌发病率快速上升,现已成为中国女性第三大高发癌症.甲状腺癌发病率的增长一部分可归因于过度筛查和诊断率的提高,然而,全球甲状腺癌病死率的显著上升和较大肿瘤诊断率的增加不能仅仅用过度诊断来解释.在本文中,笔者探讨了关于可改变的风险因素——环境暴露对甲状腺癌发病率的影响,此类原因所致的发病患者群可能正是那些非过度诊断的、体积较大的或致死性的甲状腺癌病例.在精准医疗时代,应通过流行病学调查和环境因素研究以识别这些高危甲状腺癌发病风险增加的人群.
Abstract
The incidence of thyroid cancer is rising rapidly and has now become the third most common cancer among women in China.The increase may partly result from overscreening.However,the significant rise in global mortality and increased rate of larger tumors can not be explained by overdiagnosis of microcarcinoma alone.In this review,we discuss the influence of modifiable factors,environmental exposures,on the incidence rises of throid cancer.And it caused thyroid cancer patients may be exactly those with non-overdiagnosed,larger or fatal cases.In the era of precision medicine,epidemiological investigations and environmental factor studies should be conducted to identify these populations with an increased risk of high-grade thyroid cancer.
关键词
甲状腺肿瘤/致癌物/发病率/流行病学Key words
Thyroid neoplasms/Carcinogens/Incidence/Epidemiology引用本文复制引用
出版年
2024
NETL
NSTL
万方数据