Liver regeneration(LR)is a complex set of mechanisms between liver cells and molecules in which the initiation,proliferation,and termination processes of liver repair are regulated.In the face of various liver diseases and treatment measures,the liver's regenerative capacity is significantly affected.In addition,whether liver diseases can be alleviated or even cured depends to a large extent on the regenerative ability of liver cells to achieve the recovery of liver function.Exploring the pathogenesis of LR and the related cell sources is of great significance for accelerating the recovery of liver function under different pathological modes and formulating therapeutic strategies.Although LR has been extensively studied,many challenges remain to fully understand it.This article reviews the mechanism of liver regeneration in order to have a new understanding of the changes of liver diseases and provide a new direction for the treatment of liver diseases.
关键词
肝再生/肝细胞/机制/调控
Key words
Liver Regeneration/Cell/Machine Made/Regulate and Control