摘要
目的:分析并比较腹腔镜胃镜联合手术（LECS）与开腹手术方法处理胃间质瘤（GST）的安全性和预后等临床疗效。方法:回顾性分析2017年1月至2023年4月112例根治性切除的GST患者资料，根据不同手术方式将患者分为双镜联合组（n=52例）和开腹组（n=60例）。采用SPSS26.0软件对数据进行统计分析。围手术期指标等计量资料以()表示，采用独立样本t检验；分类变量采用卡方检验；病理危险度采用秩和检验。P<0.05为差异有统计学意义。结果:所有患者手术均顺利完成，术后无死亡及相关并发症发生。与传统开腹手术相比，双镜联合组手术时间、术中出血量和术后住院时间更少(P<0.05)。结论:LECS和开腹手术切除胃间质瘤相比，手术效果相当，均可以达到根治性切除目的，但LECS具有手术时间短，术中出血量少，术后康复更快等优势，值得在临床应用上进一步推广。
Abstract
Objective:To analyze and compare the clinical efficacy of Laparoscopic and Endoscopic Cooperative Surgery (LECS) with open surgery for Gastric Stromal Tumors (GST) in terms of safety and prognosis.Methods:The data of 112 GST patients who underwent radical resection in the Department of General Surgery at the 7th Medical Center of PLA General Hospital between January 2017 and April 2023 were retrospectively collected and analyzed. According to different surgical procedures, 52 patients received LECS were divided into the combined group and 60 patients were divided into the open group who received open surgery. SPSS26.0 software was used to analyze the clinical data. The perioperative data were expressed as (), and were examined by using independent t test; categorical variables were analyzed by chi-square test and rank-sum test was used for pathological risk. A P value of <0.05 was considered as statistically significant difference.Results:The surgery was successfully completed in all patients, and no death or related complications occurred after surgery. Compared with conventional open surgery, the combined dual-mirror group had less time of surgery, intraoperative bleeding, and postoperative hospitalization (P<0.05).Conclusion:Compared with the open surgery for resection of GST, LECS has comparable therapeutic results and can achieve radical resection, but LECS has the advantages of shorter time of operation, less intraoperative bleeding, and faster postoperative recovery, which is worth further promotion in clinical application.
万方数据