Chinese Guideline for the diagnosis and management of immune monitoring after kidney transplantation
中华医学会器官移植学分会 中国医药生物技术协会移植技术分会 陈刚1
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作者信息
1. 华中科技大学同济医学院附属同济医院器官移植研究所，武汉 430030
折叠
摘要
预防肾移植排斥反应离不开免疫抑制剂，但免疫抑制过度相关的感染也会影响移植肾和移植受者的存活。主动监测肾移植受者的免疫状态有利于早期发现排斥反应风险或感染风险，有助于指导临床调整免疫抑制的强度。本指南围绕我国目前现有可行的免疫监测指标进行推荐和说明，以期有利于提高移植肾和移植受者的长期存活。 Immunosuppressive agents are essential for the prevention of renal allograft rejection, but infections associated with over immunosuppression can also affect the patient and graft survival. Regular monitoring of the recipient's immune status is conducive to early identifying the risky of rejection or infection, and can be helpful to guide clinical adjustment of immunosuppressive therapy. This guideline recommends and explains the currently available immune surveillance methods in order to ultimately improve the long-term survival of the kidney allografts and recipients.
Abstract
Immunosuppressive agents are essential for the prevention of renal allograft rejection, but infections associated with over immunosuppression can also affect the patient and graft survival. Regular monitoring of the recipient's immune status is conducive to early identifying the risky of rejection or infection, and can be helpful to guide clinical adjustment of immunosuppressive therapy. This guideline recommends and explains the currently available immune surveillance methods in order to ultimately improve the long-term survival of the kidney allografts and recipients.
关键词
肾移植/免疫监测/排斥反应/感染/供者特异性抗体/指南
Key words
Kidney transplantation/Immune surveillance/Rejection/Infection/Donor's specific antibody/Guideline
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