Kidney transplantation(KT)has been the most effective treatment of end-stage kidney disease(ESKD).With continuous improvements of transplantation technology,the proportion of patients choosing kidney re-transplantation(KR)is gradually rising.KR presents great challenges of avoiding the causes of initial graft failure,greater surgical complexity,higher risk of rejection,higher rates of postoperative infections and long-term complications,as well as heightened psychological burden.This guideline specified the indications,surgical techniques,tissue typing,postoperative follow-ups,infection prevention and other aspects of KR for boosting success rate of KR and promoting long-term survival of transplanted kidney allograft/recipient.