摘要
腔镜荧光显像系统能为腔镜外科手术提供荧光和常规白光的融合成像视野，帮助术者对术中解剖进行功能识别。吲哚菁绿(indocyanine green, ICG)是临床最常见的荧光显像剂，在普通外科手术中可用于精准标记肿瘤及手术切缘、标记前哨及肿瘤引流区域淋巴结、识别转移灶等，可提高手术效率，增加围手术期获益，降低术后并发症的发生，为手术提供保护和指导。笔者就ICG荧光显像在普通外科主要分支腔镜手术中的应用进展进行综述，结合最新研究进展，展望未来的荧光腔镜手术中3D立体成像、多色渐变、新型荧光剂等新技术的应用。
Abstract
The fluorescence imaging system under laparoscopic surgeries can provide a fused vision of fluorescence and conventional white light. Surgeons can have a more intuitive and three-dimensional image perception of the intraoperative anatomy. Indocyanine green (ICG) is the most common used clinical fluorescence imaging agent used in the field of general surgery. It has accurately marked tumors and surgical margins, demonstrated sentinel and lymph nodes in tumor drainage area, and identified metastases. Thus, ICG has the ability to improve surgical efficiency, increase perioperative benefits, reduce postoperative complications, and to provide protection and guidance for surgery. This review summarized the application of ICG fluorescence imaging in laparoscopic surgeries, including gallbladder and biliary tract surgeries, gastrointestinal surgeries, pancreatic surgeries, and thyroid/parathyroid surgeries. Recent advances are reviewed to provide future perspectives for laparoscopy fluorescence imaging, including 3D stereoscopic imaging, multicolor gradient fluorescence, and new fluorescent agents.
基金项目
中央高水平医院临床科研业务费专项(2022-PUMCH-B-003)
北京协和医学院202大学生创新训练计划项目(2022zglc06062)
万方数据