Objective:To investigate the safety and feasibility of Laennec approach for laparoscopic cholecystectomy in the treatment of type II Mirrizi syndrome.Methods:A patient with type II Mirrizi syndrome underwent laparoscopic cholecystectomy.Result:The patient was discharged on postoperative day 7 without complications. The tomogram was performed 6 weeks after surgery to assess the anatomy and exclude stones in the CBD prior to its removal.Conclusions:It is safe and feasible to treat type II Mirrizi syndrome with laparoscopic cholecystectomy via Laennec approach, more evidence is needed in large-scale clinical studies.