首页|新发难治性癫痫持续状态/热性感染相关性癫痫综合征:癫痫持续状态诊疗的新挑战

新发难治性癫痫持续状态/热性感染相关性癫痫综合征:癫痫持续状态诊疗的新挑战

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新发难治性癫痫持续状态(NORSE)及其亚类热性感染相关性癫痫综合征(FIRES)常以难治性癫痫持续状态起病,具有高病死率、高致残性的特点。由于发病机制不清,诊疗极具挑战。文中将从NORSE/FIRES定义、病因与致病机制、临床特点、治疗与预后等多个方面进行评述。
New onset refractory status epilepticus/febrile infection-related epilepsy syndrome:the new challenge in the diagnosis and treatment of status epilepticus
New onset refractory status epilepticus(NORSE)and its subcategory,febrile infection-related epilepsy syndrome(FIRES)are rare and devastating conditions,initial symptoms of which are often refractory status epilepticus.NORSE/FIRES is characterized by high mortality and disability,but unfortunately,due to the unclear pathogenesis,the diagnosis and treatment of NORSE/FIRES are very challenging.This editorial aims to summarize the key points and recent developments in the etiology,pathophysiology,diagnosis and management of these challenging conditions.

New onset refractory status epilepticusFebrile infection-related epilepsy syndromeDrug resistant epilepsyImmunological treatment

王萱、江文

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空军军医大学西京医院神经内科,西安 710032

新发难治性癫痫持续状态 热性感染相关性癫痫综合征 药物难治性癫痫 免疫治疗

国家自然科学基金

81771406

2024

中华神经科杂志
中华医学会

中华神经科杂志

CSTPCD北大核心
影响因子:1.329
ISSN:1006-7876
年,卷(期):2024.57(4)
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