New onset refractory status epilepticus/febrile infection-related epilepsy syndrome:the new challenge in the diagnosis and treatment of status epilepticus
New onset refractory status epilepticus(NORSE)and its subcategory,febrile infection-related epilepsy syndrome(FIRES)are rare and devastating conditions,initial symptoms of which are often refractory status epilepticus.NORSE/FIRES is characterized by high mortality and disability,but unfortunately,due to the unclear pathogenesis,the diagnosis and treatment of NORSE/FIRES are very challenging.This editorial aims to summarize the key points and recent developments in the etiology,pathophysiology,diagnosis and management of these challenging conditions.
New onset refractory status epilepticusFebrile infection-related epilepsy syndromeDrug resistant epilepsyImmunological treatment