Neuroimaging advances in the regression of white matter hyperintensity of presumed vascular origin
As one of the imaging features of cerebral small vessel disease,white matter hyperintensity(WMH)of presumed vascular origin is quite common in the elderly.The burden of WMH is thought to progress slowly over time and is significantly associated with cognitive decline.However,the pathogenesis of WMH remains unclear and there is no effective treatment available.Recent studies have reported that some WMH lesions can regress during follow-up,along with progression and regression occurring alternately,suggesting that longitudinal changes in WMH are not unidirectional.This article presents a systematic review of current neuroimaging studies on WMH regression to enhance the understanding of dynamic changes in WMH and to provide new theoretical evidence for WMH intervention.
Cerebral small vessel diseasesNeuroimagingCognitive dysfunctionWhite matter hyperintensity of presumed vascular originRegression
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