Research progress on the role of central cholinergic system in gait deficits and balance disturbances in Parkinson's disease
Gait deficits and balance disturbances are prevalent clinical features in Parkinson's disease(PD).There is an increasing body of evidence pointing towards the degeneration of central cholinergic neurons as a crucial factor leading to these disturbances in PD.This paper presents a comprehensive review of the relevant research on the involvement of the central cholinergic system in the mechanisms underlying gait deficits and balance disturbance in PD.The aim is to provide new perspectives and insights for the treatment of gait deficits and balance disturbances in PD.
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