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儿童失神癫痫的诊疗现状及挑战

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儿童失神癫痫(CAE)一直被认为是良性儿童期癫痫综合征。然而随着临床证据的累积,CAE患儿复杂的疾病演变、高耐药率、显著的共病比例以及意外伤害风险被逐渐发现,国内外指南观点也随之更新。文中总结目前证据及指南观点,从CAE患儿的临床特征、治疗、预后、共病以及意外伤害风险等方面进行评述,以期为CAE的临床诊疗提供一定的参考。
Current status and challenges of diagnosis and treatment in childhood absence epilepsy
Childhood absence epilepsy(CAE)has always been considered as a benign childhood epilepsy syndrome.However,with the accumulation of clinical evidence,the complex disease evolution,high incidence of pharmaco-resistance,significant comorbidity rate and risk of accidental injury in children with CAE were gradually discovered,and the views of domestic and foreign guidelines were also updated.This article reviews the current evidence and guidelines,and the clinical features,treatments,prognosis,comorbidities and accidental injury risk of children with CAE,in order to provide some reference for the clinical diagnosis and treatment of CAE.

Epilepsy,absenceChildPrognosisComorbidityClinical featuresTreatmentsRisk of accidental injury

王英藩、王小姗

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南京医科大学附属脑科医院神经内科,南京 210029

癫痫,失神性 儿童 预后 共病 临床特征 治疗 意外伤害风险

2024

中华神经科杂志
中华医学会

中华神经科杂志

CSTPCD北大核心
影响因子:1.329
ISSN:1006-7876
年,卷(期):2024.57(12)